Ana Ofelia Murguía was a Mexican actress with a long career in theater, film and television for more than 40 years. She is a graduate of the Theater School of the National Institute of Fine Arts and a student of the “father of Mexican theater” Seki Sano, which forged her for a fruitful career on stage. She received the Ariel Award for Best Female Co-Acting on four occasions for "Cadena Perpetua" (1979), "Los Motivos de Luz" (1986), "La Reina de la Noche" (1996), and the Ariel de Oro for lifetime achievement in 2011. She also won three times the Silver Goddess award for The Motifs of Light (1986), Written in the Body of the Night (2002), The Good Herbs (2011). In 2004 he received the silver Mayahuel for his career at the Guadalajara Film Festival, and in 2007 he obtained special recognition at the Lunas del Auditorio. Ana Ofelia Murguía voiced Miguel's great-grandmother in the Oscar-winning animated film Coco (2017).
| 2017 | Coco as Mamá Socorro "Coco" Rivera (voice) |
| 2013 | El mar muerto |
| 2013 | La Noria as Wife |
| 2013 | Tercera llamada |
| 2012 | Fecha de caducidad as Ramona |
| 2011 | La brújula la lleva el muerto as Doña Chelo |
| 2010 | Te extraño |
| 2010 | Las buenas hierbas as Blanquita |
| 2008 | Sólo quiero caminar as Doña Amelia |
| 2008 | Arráncame la Vida as Clarita |
| 2008 | El Viaje de la Nonna as Nonna |
| 2007 | Párpados azules as Lulita |
| 2006 | Hijas de su madre: Las Buenrostro as Doña Tere |
| 2006 | Haydutlar as Consuelo |
| 2004 | El edén |
| 2002 | Otilia Rauda as Maid |
| 2002 | La maceta |
| 2001 | Pachito Rex: Me voy, pero no del todo as Rosa María |
| 2001 | Escrito en el Cuerpo de la Noche |
| 2000 | Su alteza serenísima as La Salamandra |
| 2000 | Sexo por compasión as Vendedora de Colmado |
| 1999 | Ave María as Úrsula |
| 1998 | Luces de la noche as Doña Mary |
| 1997 | La Tarde de un Matrimonio de Clase Media as Wife |
| 1997 | De noche vienes, Esmeralda as Doña Beatriz, Jorge Luis' mother |
| 1996 | De muerte natural |
| 1996 | El Anzuelo as Doña Rosa |
| 1995 | Nadie hablará de nosotras cuando hayamos muerto as Doña Amelia |
| 1995 | Morena |
| 1994 | La reina de la noche as Doña Victoria |
| 1994 | Ámbar as Frau Buschberger |
| 1994 | El jardín del Edén as Juana |
| 1992 | Mi querido Tom Mix as Joaquina |
| 1992 | Objetos Perdidos as Neighbor woma |
| 1991 | El jinete de la divina providencia |
| 1991 | One Man’s War as Doña Teresa |
| 1990 | Morir en el golfo as Chiara |
| 1989 | Goitia, un dios para sí mismo as Juana |
| 1989 | Intimidad |
| 1989 | Las asesinas del panadero as Jovita |
| 1987 | Gaby: A True Story as Nurse at Brimmer House |
| 1987 | Los confines as Madre de Natalia |
| 1986 | ¿Cómo Ves? as Mother |
| 1986 | Chido Guan, el tacos de oro as Doña Meche |
| 1986 | Las inocentes as Chief Nun |
| 1985 | Mexicano ¡Tú puedes! as Burócrata |
| 1985 | Los motivos de Luz as Luz's mother in law |
| 1984 | Dune as Palace Maid (uncredited) |
| 1984 | El corazón de la noche as La Alumna |
| 1982 | La víspera |
| 1981 | 'Ora Sí ¡Tenemos Que Ganar! |
| 1980 | Constelaciones as Juana Inés de la Cruz |
| 1979 | Cadena perpetua as Mrs. Romero |
| 1979 | María de mi Corazón as Doctora Murguía |
| 1978 | Naufragio as Amparo |
| 1978 | Pedro Páramo, el hombre de la Media Luna as Damiana Cisneros |
| 1978 | Amor libre as Esposa de Ernesto |
| 1977 | La viuda negra |
| 1977 | Maten al León as Esperanza de Pereira |
| 1976 | Las poquianchis as Eva |
| 1976 | El Apando as Celadora |
| 1976 | Mexico, Mexico, ra, ra, ra! |
| 1975 | Esa mi Irene |
| 1973 | El Profeta Mimí as Catita |
| 1971 | El águila descalza as Trabajadora factoria |
| 1971 | Para servir a usted |
| 1970 | El juego de Zuzanka as Voz de Zuzanka (voice) |
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